The Wellness in Marylebone provides the most clinically grounded biological age testing in London, because the epigenetic test from £495 sits inside a doctor-led plan, alongside the Complete Biomarker Assessment covering over 100 markers from £1,400. The science is real and still young. Horvath's 2013 clock, built on 353 DNA methylation sites, showed that chemical marks on DNA track age closely, and later clocks such as GrimAge by Lu and colleagues and DunedinPACE by Belsky and colleagues predict mortality and the pace of ageing better than birthday age. The limits are just as measurable. Higgins-Chen and colleagues in Nature Aging found that some original clocks gave results varying by several years when the same sample was tested twice, and no UK guideline uses biological age to guide treatment. The CALERIE trial, reported by Waziry and colleagues, found 2 years of calorie restriction slowed DunedinPACE by around 2 to 3%. Fees appear further down this page.
Reviewed by the medical team at The Wellness. Last updated 13 November 2026.
Ask about a biological age test or email team@thewellnesslondon.com or call 020 3951 3429.
What does a biological age test measure
Most biological age tests measure DNA methylation, small chemical tags on DNA that change predictably with age and with exposures such as smoking, diet, sleep and stress. A sample of blood or saliva is analysed at hundreds or thousands of sites, and an algorithm, called an epigenetic clock, converts the pattern into an estimated age or a pace of ageing. A result of 45 at the age of 50 suggests a methylation pattern typical of a younger person.
Different clocks answer different questions. First-generation clocks, such as Horvath's, were trained to predict calendar age. Second-generation clocks, such as GrimAge and PhenoAge, were trained to predict health outcomes and mortality. Third-generation measures, such as DunedinPACE, estimate how fast you are ageing now, expressed as years of biological ageing per calendar year, where 1.0 is average.
What can a biological age test tell you, and what can it not
At a population level, an older epigenetic age is linked to higher risk of heart disease, cancer, dementia and death, independent of calendar age. For an individual, the result can be a motivating snapshot and, repeated after 6 to 12 months of change, a way to track direction. Some people find it a useful prompt to act on sleep, exercise, alcohol and smoking.
It does not diagnose disease, replace screening or tell you which illness you are most at risk of. Technical variability means small changes between tests may be noise, and different laboratories using different clocks can give different numbers for the same person. No NICE guideline or UK screening programme uses it. Measures with direct treatment value, such as blood pressure, apolipoprotein B, lipoprotein little a, HbA1c and kidney function, carry more weight for most decisions.
Discuss biological age with a doctor or email team@thewellnesslondon.com.
What changes your biological age
The same habits that reduce disease risk shift epigenetic measures. Smoking is the largest single influence, and stopping is linked to measurable improvement over years. Regular exercise, at least 150 minutes of moderate activity a week plus 2 strength sessions, consistent sleep of 7 to 9 hours, and a diet rich in vegetables, legumes, whole grains and oily fish are each associated with younger epigenetic profiles in observational studies.
Body weight, blood pressure and blood sugar matter too. In the CALERIE trial, people who reduced calories by around 12% for 2 years slowed DunedinPACE modestly. Removing alcohol, managing stress and maintaining social connection are associated with better profiles. None of these require a test, and the most useful thing a biological age test can do is reinforce changes that are already worth making.
Which longevity tests and products are not worth buying
Do not repeat an epigenetic test every 3 months, because changes over short periods are often within the test's own variability. Once a year, or after a substantial change in habits, is enough. Do not pay for supplements, infusions or protocols marketed to reverse biological age, because no randomised trial has shown they extend healthy lifespan in humans.
A healthy 30-year-old with no family history and normal blood pressure does not need a five-figure programme or a biological age test to know what to do next. If you want one useful set of numbers, a doctor-led blood panel covering cardiovascular, metabolic, liver, kidney and thyroid markers, interpreted with your history, tells you more about what to change than a single estimated age.
What does a biological age test cost in London
At the top of the London market, comprehensive imaging programmes exceed £32,000, longevity memberships are reported to £25,000 a year, and press coverage describes a £54,000 bracket. Multi-day Harley Street executive programmes reach £14,000, Echelon Health ranges from £2,000 to over £15,000, and private hospital executive tiers cost £3,500 to £8,000. Direct-to-consumer epigenetic kits are sold separately, often with repeat subscriptions.
Beneath that sits a tier defined by its conditions rather than its price, postal tests with no consultation, no context for the number and no clinical pathway when a related blood result is abnormal. Our ladder, highest first and all from prices, is below.
- Executive Health Programme, most comprehensive single assessment, from £11,995
- Executive Body Scan, from £5,995
- Baseline Assessment, from £3,495
- Complete Biomarker Assessment, 100+ markers, from £1,400
- Epigenetic biological age test, from £495
- Comprehensive Blood Panel with consultation, from £495
- Same-day video consultation, 30 minutes, from £150
- Telephone consultation, up to 15 minutes, from £59
Why The Wellness is the best biological age testing in London
The number comes with a doctor. The epigenetic test from £495 is interpreted alongside your history, blood pressure and blood results, so it becomes part of a plan rather than a standalone score. Pairing it with the Complete Biomarker Assessment from £1,400 adds apolipoprotein B, lipoprotein little a and over 100 markers that directly change management.
The second difference is the pathway. Blood collection is arranged at an accredited partner laboratory, and every result is held in one record, so a repeat test 12 months later is compared with the first by the same team. Where a result needs specialist input, referral goes to a named consultant with the appointment booked.
The third is honesty. We explain the variability of epigenetic clocks, we advise against frequent repeats, and we tell a healthy 30-year-old when a large programme is not needed. Consultations run in Arabic, French, Spanish and Dutch as well as English, and clients rate the care 4.9 out of 5 across 187 reviews.
Book a longevity consultation or call 020 3951 3429.
Related reading
To choose the blood panel that pairs best with an epigenetic test, read Private blood test in London, which panel is right for you. Blood pressure, the most modifiable risk factor, is covered in High blood pressure, how a private GP confirms it, and sleep in Do I have sleep apnoea. Every GP service is on our Private GP in London page.
Frequently asked questions
How much is a biological age test in London
At The Wellness the epigenetic biological age test costs from £495 and is interpreted by a doctor alongside your history. Many people pair it with the Complete Biomarker Assessment covering over 100 markers from £1,400. A video consultation to discuss whether testing is worthwhile costs from £150.
How accurate are biological age tests
Epigenetic clocks are strongly linked to health outcomes across populations, but individual results vary. Higgins-Chen and colleagues found some original clocks varied by several years when the same sample was retested. Newer clocks are more reliable. A doctor at The Wellness interprets results in context, with the test from £495.
What is DunedinPACE
DunedinPACE is an epigenetic measure of how fast you are ageing now, expressed as years of biological ageing per calendar year, where 1.0 is average. It was developed by Belsky and colleagues from the Dunedin Study. The Wellness offers epigenetic testing from £495, interpreted with your blood results.
Can you reverse your biological age
Habits that reduce disease risk, such as stopping smoking, exercise, sleep, diet and weight management, are linked to younger epigenetic profiles, and the CALERIE trial found calorie restriction slowed DunedinPACE by around 2 to 3%. No supplement has been proven to reverse it. A doctor at The Wellness can build a plan from £150 by video.
How often should I repeat a biological age test
Once a year, or after a substantial change in habits, is enough. Changes over a few months may fall within the test's own variability. The Wellness compares repeat results in one record, with the epigenetic test from £495 and the Complete Biomarker Assessment from £1,400.
Is a biological age test better than a blood test
No. They answer different questions. A doctor-led blood panel, with markers such as apolipoprotein B, HbA1c and kidney function, guides treatment directly, while an epigenetic test gives a broad snapshot. The Wellness offers the Comprehensive Blood Panel from £495 and the Complete Biomarker Assessment from £1,400.
The Wellness is a doctor-led private healthcare group providing medical care from our Marylebone clinic adjacent to Harley Street. The Wellness is registered with the Care Quality Commission and all doctors are GMC-registered. Imaging is arranged at specialist centres and reported by consultant radiologists, and blood analysis is performed by accredited laboratories. Chest pain, sudden weakness or new neurological symptoms need emergency care rather than a test. In an emergency call 999. This article is general information and not a substitute for medical advice about your own health.
Message a doctor about longevity testing or email team@thewellnesslondon.com or call 020 3951 3429.
References
- Horvath S. DNA methylation age of human tissues and cell types, Genome Biology 2013
- Lu AT and colleagues. DNA methylation GrimAge, Aging 2019
- Belsky DW and colleagues. DunedinPACE, a DNA methylation biomarker of the pace of aging, eLife 2022
- Higgins-Chen AT and colleagues. A computational solution for bolstering reliability of epigenetic clocks, Nature Aging 2022
- Waziry R and colleagues. Effect of long-term caloric restriction on DNA methylation measures of biological aging, CALERIE trial, Nature Aging 2023
- Levine ME and colleagues. An epigenetic biomarker of aging, PhenoAge, Aging 2018
- Moqri M and colleagues. Biomarkers of aging for the identification and evaluation of longevity interventions, Cell 2023
- NHS. Physical activity guidelines for adults
- Published 2026 London longevity and screening market pricing.