The Wellness in Marylebone provides the most structured private assessment of persistent tiredness in London, with a same-day video consultation from £150, a Targeted Blood Panel from £295 and the Complete Biomarker Assessment covering over 100 markers from £1,400, against private consultant first appointments of £250 to £500. Tiredness is one of the commonest reasons adults see a doctor, and the Royal College of Psychiatrists estimates around 1 in 5 people feel unusually tired at any one time. The cause is usually found in the history rather than the blood. In the VAMPIRE trial, Koch and colleagues followed 325 people with new unexplained fatigue in general practice and found a physical illness detectable by blood tests in 8%, while larger test sets mainly added false positives. The tests that matter are well defined. NICE CKS recommends a full blood count, ferritin, kidney, liver and thyroid function, HbA1c, inflammatory markers and coeliac antibodies for unexplained fatigue, and a ferritin below 30 micrograms per litre confirms iron deficiency in most adults. Reverse T3, adrenal fatigue saliva tests and IV vitamin drips are not on that list. Fees appear further down this page.
Reviewed by the medical team at The Wellness. Last updated 13 November 2026.
Find the cause of your tiredness or email team@thewellnesslondon.com or call 020 3951 3429.
Why am I tired all the time
The commonest causes are lifestyle and mood rather than disease. Too little sleep, irregular hours, shift work, long working weeks, caring responsibilities, alcohol, caffeine late in the day, and low activity all cause tiredness that improves when the pattern changes. Stress, anxiety and depression cause fatigue that sleep does not fix, often with poor concentration and loss of interest.
Physical causes are less common but important. They include iron deficiency anaemia, an underactive thyroid, diabetes, vitamin B12 or folate deficiency, coeliac disease, sleep apnoea, kidney or liver disease, medicines such as beta blockers and antihistamines, and the recovery period after infections. Fatigue lasting more than 6 weeks after a viral illness, worsened by exertion, may be post-viral fatigue or ME/CFS, which NICE NG206 addresses.
Which tests does a private GP arrange for tiredness
You are assessed first. The doctor asks about sleep, mood, work, alcohol, diet, periods, weight change, medicines, recent infections and other symptoms, and examines you. Blood tests are then chosen from the NICE CKS list, full blood count, ferritin, kidney and liver function, thyroid function, HbA1c, CRP or ESR, and coeliac antibodies, with vitamin B12, folate and vitamin D where the history suggests them.
Blood collection is arranged separately at an accredited partner laboratory, a short walk from the clinic or near you, and a further review appointment goes through every result together. If tests suggest sleep apnoea, a home sleep study can be arranged. If they are normal, the most useful outcome is a clear plan for sleep, activity and mood, and a date to review progress, usually in 4 to 6 weeks.
Book a tiredness consultation or email team@thewellnesslondon.com.
What can I do about tiredness right now
Start with sleep. Aim for 7 to 9 hours with the same wake time every day, including weekends, keep the bedroom dark and cool, and stop caffeine after midday. Remove alcohol, which fragments sleep even when it helps you fall asleep. Get outside in daylight within an hour of waking, which strengthens the body clock and improves alertness.
Move more, even when you feel tired. Building up to 150 minutes of moderate activity a week improves energy for most people within 4 to 8 weeks, although people with post-viral fatigue or ME/CFS should pace activity carefully, as NICE NG206 advises, rather than push through. Eat regular meals with protein and iron-rich foods, and if your periods are heavy, tell your doctor, because heavy bleeding is the commonest cause of iron deficiency in women.
Which tiredness tests and treatments are not worth buying
Reverse T3, adrenal fatigue saliva cortisol tests and hair mineral analysis are not recommended for investigating tiredness, because they do not diagnose any recognised condition and lead to unnecessary treatment. Large direct-to-consumer panels without a consultation often generate borderline results that cause worry without explaining fatigue.
IV vitamin drips and B12 injections help only when a deficiency is proven, and iron should not be taken without a test, because excess iron is harmful. Thyroid hormone should never be started without an abnormal thyroid test. If your blood tests are normal, paying for more tests is rarely the answer. Sleep, activity, mood and workload almost always matter more.
What does a tiredness assessment cost in London
At the top of the London market, comprehensive imaging programmes exceed £32,000, multi-day Harley Street executive programmes reach £14,000 and private hospital executive tiers cost £3,500 to £8,000. Private consultant first appointments run £250 to £500, and Harley Street GP consultations £250 to £350, before any blood test is added.
Beneath that sits a tier defined by its conditions rather than its price, home finger-prick kits with no consultation, no examination and no clinical pathway when a result is abnormal. Our fees, all from prices, are below.
- Complete Biomarker Assessment, 100+ markers, from £1,400
- Sleep assessment with home study, from £1,295
- Home, hotel or office visit, evenings and weekends, from £695
- Comprehensive Blood Panel with consultation, from £495
- Extended 45-minute consultation, from £395
- Targeted Blood Panel, from £295
- In-person consultation, 30 minutes, from £220
- Same-day video consultation, 30 minutes, from £150
- Telephone consultation, up to 15 minutes, from £59
Why The Wellness is the best tiredness assessment in London
The history comes before the tests. A same-day video consultation from £150 lasts 30 minutes, 3 times a standard 10-minute NHS appointment, which is the time it takes to separate sleep, mood and workload from iron deficiency or thyroid disease. Your allocated doctor then specifies the tests from the NICE list rather than a generic panel.
The second difference is follow-through. Blood collection is arranged at an accredited partner laboratory, every result returns to one record, and a further review appointment explains what the results mean and agrees a plan. Where a specialist is needed, such as a sleep physician, gastroenterologist or endocrinologist, referral goes to a named consultant with the appointment booked.
The third is honesty. We tell you that reverse T3 and adrenal fatigue tests are not worth buying, and that most tiredness improves with changes you can start today. Consultations run in Arabic, French, Spanish and Dutch as well as English, and clients rate the care 4.9 out of 5 across 187 reviews.
Start a tiredness assessment or call 020 3951 3429.
Related reading
Snoring with daytime sleepiness may be sleep apnoea, covered in Do I have sleep apnoea. Choosing the right blood panel is explained in Private blood test in London, which panel is right for you, and low mood in Anxiety, stress and low mood, how a private GP can help. Every GP service is on our Private GP in London page.
Frequently asked questions
What blood tests should I have if I am always tired
NICE CKS recommends a full blood count, ferritin, kidney and liver function, thyroid function, HbA1c, CRP or ESR and coeliac antibodies, with vitamin B12, folate and vitamin D where the history suggests them. At The Wellness a Targeted Blood Panel costs from £295 and a Comprehensive Blood Panel with consultation from £495.
When should I see a doctor about tiredness
See a doctor if tiredness lasts more than 4 weeks, affects daily life, or comes with weight loss, night sweats, breathlessness, heavy periods, low mood or snoring with pauses in breathing. The Wellness offers same-day video consultations from £150 and in-person appointments from £220.
Can low iron cause tiredness without anaemia
Yes. Ferritin below 30 micrograms per litre indicates iron deficiency in most adults, and it can cause tiredness before haemoglobin falls. Heavy periods are the commonest cause in women. A doctor at The Wellness can test ferritin within a Targeted Blood Panel from £295.
Is adrenal fatigue real
Adrenal fatigue is not a recognised medical diagnosis, and saliva cortisol tests marketed for it are not recommended. True adrenal insufficiency is rare and diagnosed with specific blood tests. A doctor at The Wellness can assess tiredness properly, from £150 by video.
What is the most common cause of tiredness
Most persistent tiredness is linked to sleep, stress, mood, workload, alcohol and activity, and in the VAMPIRE trial blood tests found a physical illness in 8% of people with unexplained fatigue. Blood tests still matter to rule out treatable causes. The Wellness offers assessment from £150 by video.
What is ME/CFS
ME/CFS is a long-term condition with fatigue that worsens after physical or mental exertion, unrefreshing sleep and cognitive difficulties, lasting at least 3 months. NICE NG206 advises pacing activity rather than graded exercise. A doctor at The Wellness can assess symptoms and refer to a named specialist, from £150 by video.
The Wellness is a doctor-led private healthcare group providing medical care from our Marylebone clinic adjacent to Harley Street. The Wellness is registered with the Care Quality Commission and all doctors are GMC-registered. Imaging is arranged at specialist centres and reported by consultant radiologists, and blood analysis is performed by accredited laboratories. Tiredness with breathlessness at rest, chest pain, fainting or thoughts of self-harm needs urgent care. In an emergency call 999. This article is general information and not a substitute for medical advice about your own health.
Ask a doctor about tiredness or email team@thewellnesslondon.com or call 020 3951 3429.
References
- NICE CKS. Tiredness and fatigue in adults
- NICE NG206. Myalgic encephalomyelitis or chronic fatigue syndrome
- Koch H and colleagues. Ordering blood tests for patients with unexplained fatigue in general practice, VAMPIRE trial, British Journal of General Practice 2009
- Royal College of Psychiatrists. Tiredness and fatigue
- British Society of Gastroenterology. Guidelines for the management of iron deficiency anaemia in adults
- NICE NG145. Thyroid disease, assessment and management
- Society for Endocrinology. Adrenal fatigue position
- NHS. Tiredness and fatigue
- Published 2026 London private GP and blood testing market pricing.